User:Avinash S. Punekar/Sandbox 1
From Proteopedia
Introduction
Post-transcriptional modification of ribosomal RNA (rRNA) occurs in all living organisms. In bacteria, rRNA modifications are done by site-specific enzymes. One such rRNA modification enzyme is a S-adenosyl-L-methionine (SAM) dependent methyltransferase RlmJ. The biochemical experiments showed that the Escherichia coli RlmJ transfers a methyl group from SAM to the exocyclic nitrogen N6 of adenosine A2030 (m6A2030) in the 23S rRNA [1].
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References
- ↑ Golovina AY, Dzama MM, Osterman IA, Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA. The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA. RNA. 2012 Sep;18(9):1725-34. doi: 10.1261/rna.034207.112. Epub 2012 Jul 30. PMID:22847818 doi:10.1261/rna.034207.112
