Phospholipase A2 homolog

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Phospholipase A2 homolog dimer complex with inhibitor suramin, PEG400, pentaethylene glycol and sulfate (PDB code 4yv5)

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3D structures of phospholipase A2 homolog

Updated on 14-December-2021


References

  1. Lomonte B, Angulo Y, Sasa M, Gutierrez JM. The phospholipase A2 homologues of snake venoms: biological activities and their possible adaptive roles. Protein Pept Lett. 2009;16(8):860-76. doi: 10.2174/092986609788923356. PMID:19689412 doi:http://dx.doi.org/10.2174/092986609788923356
  2. Salvador GH, Dreyer TR, Cavalcante WL, Matioli FF, Dos Santos JI, Velazquez-Campoy A, Gallacci M, Fontes MR. Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin. Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2066-78. doi:, 10.1107/S1399004715014443. Epub 2015 Sep 26. PMID:26457430 doi:http://dx.doi.org/10.1107/S1399004715014443

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