Structural highlights
Function
ZFY16_HUMAN May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.[1] [2]
References
- ↑ Seet LF, Hong W. Endofin, an endosomal FYVE domain protein. J Biol Chem. 2001 Nov 9;276(45):42445-54. Epub 2001 Sep 6. PMID:11546807 doi:http://dx.doi.org/10.1074/jbc.M105917200
- ↑ Seet LF, Liu N, Hanson BJ, Hong W. Endofin recruits TOM1 to endosomes. J Biol Chem. 2004 Feb 6;279(6):4670-9. Epub 2003 Nov 12. PMID:14613930 doi:http://dx.doi.org/10.1074/jbc.M311228200