1jr4, resolution 2.63Å
[COMT_RAT] Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
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Categories: Buffalo rat | Catechol O-methyltransferase | Ruf, A | Stihle, M | Bisubstrate inhibitor | Methyltransferase | Neurotransmitter degradation | Transferase