Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
2pd4 is a 4 chain structure with sequence from Helicobacter pylori. This structure supersedes the now removed PDB entry 1jw7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
FABI_HELPY Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.