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User:Michael Strong/TB

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Web Supplement to:
Comprehensive Structural Analysis of Drug-Resistant Mutations in Mycobacterium tuberculosis.

Michael Strong 1,2, Andreas Sandgren 3,4, James E. Galagan 5,6, Mark Borowsky 5,7,8, George M. Church 2, Megan B. Murray 3,

1.Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206,
2.Department of Genetics, Harvard Medical School, Boston, MA 02115,
3.Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115,
4.European Centre for Disease Prevention and Control,
5.Broad Institute of MIT and Harvard, Cambridge, MA, 02142,
6.College of Engineering, Boston University, Boston, MA, 02118,
7.Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, 02114,
8.Department of Genetics, Massachusetts General Hospital, Boston, MA, 02114.

Correspondence regarding this webpage can be sent to: StrongM@NJHealth.org

Please click on the GREEN links to see the structural details described.



Contents

RpoB homology model with Rifampin bound

RpoB Homology Model with Rifampin bound











GidB homology model with S-adenosylmethionine bound

GidB homology model with S-adenosylmethionine bound










RpsL homology model with streptomycin

RpsL homology model with streptomycin











InhA crystal structure with ETH-NAD bound

InhA with ETH-NAD, X-ray Crystal Structure 2h9i














InhA crystal structure with INH-NAD bound

InhA with INH-NAD, X-ray Crystal Structure 2nv6














GyrA crystal structure

GyrA X-ray Crystal Structure 3ILW











KatG crystal structure with heme bound

KatG, X-ray Crystal Structure 2cca












PncA crystal structure

PncA, X-ray Crystal Structure 3GBC


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Michael Strong

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