Thrombin

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Human thrombin large (red) and small (green) subunits complex with prolinamide derivative (PDB code 1ppb)

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References

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  13. Saenko EL, Shima M, Sarafanov AG. Role of activation of the coagulation factor VIII in interaction with vWf, phospholipid, and functioning within the factor Xase complex. Trends Cardiovasc Med. 1999 Oct;9(7):185-92. PMID:10881749
  14. Camire, R. M. (2010). Platelet factor V to the rescue. Blood, 115(4), 753-754. DOI: 10.1182/blood-2009-11-252619
  15. Berkner KL. Vitamin K-dependent carboxylation. Vitam Horm. 2008;78:131-56. doi: 10.1016/S0083-6729(07)00007-6. PMID:18374193 doi:http://dx.doi.org/10.1016/S0083-6729(07)00007-6
  16. 16.0 16.1 16.2 16.3 16.4 16.5 16.6 16.7 Lechtenberg BC, Freund SM, Huntington JA. An ensemble view of thrombin allostery. Biol Chem. 2012 Sep;393(9):889-98. doi: 10.1515/hsz-2012-0178. PMID:22944689 doi:http://dx.doi.org/10.1515/hsz-2012-0178
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  25. Spronk HM, Borissoff JI, ten Cate H. New insights into modulation of thrombin formation. Curr Atheroscler Rep. 2013 Nov;15(11):363. doi: 10.1007/s11883-013-0363-3. PMID:24026641 doi:http://dx.doi.org/10.1007/s11883-013-0363-3

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Michal Harel, Alexander Berchansky, Cody Couperus, Joel L. Sussman

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