First time at Proteopedia? Click on the green links: they change the 3D image. Click and drag the molecules. Proteopedia is a 3D, interactive encyclopedia of proteins, RNA, DNA and other molecules. With a free user account, you can edit pages in Proteopedia. Visit the Main Page to learn more.

From Proteopedia

Crystal Structure of Ribosomal protein THX from 2zm6, chain V

Ribosomal protein THX from 2zm6, chain V
Sites:	and
Ligands:
Related:	2e5l, 2hhh
Structural annotation: Resources: InterPro : Ipr001865, Ipr018130, Ipr005706, Ipr015946, Ipr018280, Ipr009019, Ipr008282, Ipr005704, Ipr004087, Ipr004044, Ipr001351, Ipr002942, Ipr005709, Ipr018079, Ipr001912, Ipr014720, Ipr018192, Ipr013810, Ipr014721, Ipr005712, Ipr005324, Ipr000851, Ipr014717, Ipr000529, Ipr005717, Ipr000235, Ipr000630, Ipr000754, Ipr001848, Ipr005731, Ipr018268, Ipr018102, Ipr001971, Ipr019981, Ipr016027, Ipr006032, Ipr005679, Ipr019980, Ipr001892, Ipr018269, Ipr010979, Ipr018271, Ipr001209, Ipr000589, Ipr005290, Ipr009068, Ipr000307, Ipr019984, Ipr019979, Ipr000266, Ipr012340, Ipr018275, Ipr018170, Ipr001648, Ipr002222, Ipr005732, Ipr002583 Pfam : PF00318, PF00189, PF07650, PF00417, PF01479, PF00163, PF03719, PF00333, PF01250, PF00177, PF00410, PF00380, PF00338, PF00411, PF00164, PF00416, PF00253, PF00312, PF00886, PF00366, PF01084, PF00203, PF01649 UniProt : P80371, P80372, P80373, Q5SHQ5, Q5SLP8, P17291, Q5SHQ2, P80374, Q5SHN7, P80376, Q5SHN3, P80377, Q5SHQ1, Q5SJ76, Q5SJH3, Q5SHP7, Q5SLQ0, Q5SHP2, P80380, Q5SIH3
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB, TOPSAN
Coordinates:	save as pdb, mmCIF, xml

Ribosomal protein THX is one of the 22 proteins which belong to the of the bacterial ribosome. It stabilizes a number of RNA elements and belongs to the RPS31E family. The images at the left and at the right correspond to one representative Ribosomal protein THX, i.e. the crystal structure of Ribosomal protein THX from Thermus thermophilus (2zm6, chain V).

3D Structures of Ribosomal protein THX

Update December 2011

THX in small ribosomal subunit

2zm6, 1n36, 1j5e, 3oge, 3ogy, 3ohc, 3ohd, 3oi0, 3oi4, 3oto - TtTHX in 30S ribosomal subunit+16S RRNA - Thermus thermophilus
2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub - TtTHX in 30S ribosomal subunit+16S RRNA+RNA fragment
1i94 - TtTHX in 30S ribosomal subunit+16S RRNA
3pyn, 3pyq, 3pys, 3pyu - TtTHX in 30S ribosomal subunit+16S RRNA + RNA domain 3

THX in small + large ribosomal subunit

1ml5 - EcTHX in 30S ribosomal subunit+50S ribosomal subunit+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

THX in small ribosomal subunit+ chain release factor

3mr8, 3ms0 – TtTHX in 30S ribosomal subunit+chain release factor 1+P-site tRNA+mRNA+16S RRNA
3d5a, 3d5c - TtTHX in 30S ribosomal subunit+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA
2b64 - TtTHX in 30S ribosomal subunit+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1
2b9m - TtTHX in 30S ribosomal subunit+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2
2x9r, 2x9t, 2wh1, 2wh3 - TtTHX in 30S ribosomal subunit+chain release factor 2+P-site tRNA+mRNA +16S RRNA
3f1e, 3f1g - TtTHX in 30S ribosomal subunit+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
3zvo – TtTHX in 30S ribosomal subunit+P-site tRNA Met +mRNA +16S RRNA+chain release factor 3

THX in small ribosomal subunit+tRNA+mRNA

2hgi - TtTHX in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet
2hgp - TtTHX in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
2hgr - TtTHX in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA
1yl4 – TtTHX in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator
1xnq, 1xnr - TtTHX in 30S ribosomal subunit+mRNA+tRNA anticodon+16S RRNA

THX in small ribosomal subunit+A-site tRNA

2uxd, 2uxc - TtTHX in 30S ribosomal subunit+A-site mRNA CGGG+tRNA anticodon+16S RRNA
1n32, 1n33 - TtTHX in 30S ribosomal subunit+A-site mRNA fragment+tRNA anticodon+16S RRNA
1n34 - TtTHX in 30S ribosomal subunit+A-site mRNA fragment +16S RRNA
1xmo, 1xmq - TtTHX in 30S ribosomal subunit+A-site mRNA+tRNA anticodon+16S RRNA
2uxb - TtTHX in 30S ribosomal subunit+A-site mRNA GGGU+tRNA anticodon+16S RRNA

THX in small ribosomal subunit+P-site tRNA

3i8g - TtTHX in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
3i8h, 3i9b, 3i9d - TtTHX in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
1ibk - TtTHX in 30S ribosomal subunit+P-site mRNA fragment +16S RRNA

THX in small ribosomal subunit+A-site tRNA+P-site tRNA

1ibl, 1ibm - TtTHX in 30S ribosomal subunit+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

THX in small ribosomal subunit+P-site tRNA+E-site tRNA

2ow8 - TtTHX in 30S ribosomal subunit+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA
2b9o - TtTHX in 30S ribosomal subunit+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA
2qnh - TtTHX in 30S ribosomal subunit+P-site tRNA+E-site tRNA+mRNA +16S RRNA

THX in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

1jgo, 1jgp, 1jgq, 1gix - TtTHX in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA

THX in small ribosomal subunit + antibiotics

1i95, 1i97, 3ohy, 3oi2, 2hhh - TtTHX in 30S ribosomal subunit+16S RRNA+ antibiotic
1hnw, 1hnx, 1hnz , 1fjg- TtTHX in 30S ribosomal subunit+16S RRNA+mRNA fragment+ antibiotic
2qbb, 2qb9 - EcTHX in 30S ribosomal subunit+16S RRNA+antibiotic
2j00, 2j02, 2wdg, 2wdh, 2wdk, 2wdm, 3knj, 3knh, 3knl, 3knn - TtTHX in 30S ribosomal subunit+16S RRNA+ antibiotic -P-site tRNA fMet+E-site tRNA Phe+mRNA

THX in small ribosomal subunit + ribosome recycling factor

2v46, 2v48 - TtTHX in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

THX in small ribosomal subunit + elongation factor

2wri, 2wrk - TtTHX in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA+elongation factor G
2wrn, 2wrq - TtTHX in 30S ribosomal subunit+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4
3fic - TtTHX in 30S ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A
3huw, 3huy - TtTHX in 30S ribosomal subunit+tRNA-Met+mRNA +16S RRNA+elongation factor P
2y0u, 2y0w, 2y0y, 2y0x - TtTHX in 30S ribosomal subunit+A-site tRNA +E-site tRNA+mRNA codon+16S RRNA+elongation factor TU
2y10, 2y12, 2y14, 2y16, 2y18 - TtTHX in 30S ribosomal subunit+A-site tRNA+P-site tRNA +mRNA codon+16S RRNA+elongation factor TU

THX in small ribosomal subunit + translation initiation factor

1i96 - TtTHX in 30S ribosomal subunit+IF3+16S RRNA
1hr0 - TtTHX in 30S ribosomal subunit+IF+16S RRNA

THX in small ribosomal subunit + various proteins

3kiq, 3kis, 3kiu, 3kix - TtTHX in 30S ribosomal subunit+toxin RelE+16S RRNA
2xfz, 2xg1 - TtTHX in 30S ribosomal subunit+tRNA Phe+mRNA+colicin E3+16S RRNA