HMG-CoA Reductase

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This page was featured in the Journal of Biochemistry and Molecular Biology Education as it appeared on December 23, 2010.

Crystal Structure of HMG-CoA, (PDB code 1dq8)

Contents

3D Structures of HMG-CoA Reductase

Updated on 18-August-2014

HMGCR

1r7i, 4i64 - PmHMGCR catalytic domain - Pseudomonas mevalonii
3qae, 3qau - HMGCR (mutant) - Streptococcus pneumoniae

HMGCR+statins

3cct, 3ccw, 3ccz, 3cd0, 3cd5, 3cd7, 3cda, 3cdb, 2r4f, 3bgl, 2q1l, 2q6b, 2q6c, 1hw8, 1hw9, 1hwi, 1hwj, 1hwk, 1hwl – hHMGCR catalytic domain + statin derivatives - human
1t02 - PmHMGCR catalytic domain + statin derivatives

HMGCR+cofactors

1r31 – PmHMGCR catalytic domain +CoA+mevalonate
1qax, 4i4b - PmHMGCR catalytic domain +HMG+CoA+NAD+
4i56 - PmHMGCR catalytic domain + dithio-HMG+CoA
4i6a - PmHMGCR catalytic domain + HMG+CoA
4i6w - PmHMGCR catalytic domain + thiomevalonate
4i6y - PmHMGCR catalytic domain + mevalonate
1qay - PmHMGCR catalytic domain +mevalonate+NAD+
1dq8 - hHMGCR catalytic domain (mutant) +CoA+HMG
1dq9 - hHMGCR catalytic domain (mutant)+HMG-CoA
1dqa - hHMGCR catalytic domain (mutant)+HMG+CoA+NADP+

Additional Resources

References

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