4fvj

Structural highlights

Function

STOM_MOUSE Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.^{[1] [2]}

References

1. ↑ Price MP, Thompson RJ, Eshcol JO, Wemmie JA, Benson CJ. Stomatin modulates gating of acid-sensing ion channels. J Biol Chem. 2004 Dec 17;279(51):53886-91. Epub 2004 Oct 7. PMID:15471860 doi:http://dx.doi.org/10.1074/jbc.M407708200
2. ↑ Brand J, Smith ES, Schwefel D, Lapatsina L, Poole K, Omerbasic D, Kozlenkov A, Behlke J, Lewin GR, Daumke O. A stomatin dimer modulates the activity of acid-sensing ion channels. EMBO J. 2012 Jul 31. doi: 10.1038/emboj.2012.203. PMID:22850675 doi:10.1038/emboj.2012.203