4e15

Structural highlights

Function

KFA_DROME Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.[HAMAP-Rule:MF_03014]^{[1] [2]}

References

1. ↑ Han Q, Robinson H, Li J. Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. Biochem J. 2012 Jun 12. PMID:22690733 doi:10.1042/BJ20120416
2. ↑ Moore GP, Sullivan DT. Biochemical and genetic characterization of kynurenine formamidase from Drosophila melanogaster. Biochem Genet. 1978 Aug;16(7-8):619-34. PMID:83140