3kam
From Proteopedia
Hen Egg White Lysozyme Derivatized with rhenium(I) diaquatricarbonyl cation
Structural highlights
FunctionLYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedThe reaction of Re(CO)(3)(H(2)O)(3)(+) with hen egg lysozyme in aqueous solution results in a single covalent adduct; single crystal X-ray diffraction shows that the rhenium tricarbonyl cation binds to His15 in two significantly populated rotamer conformations. Specific derivatization of lysozyme in aqueous solution with Re(CO)3(H2O)3(+).,Binkley SL, Ziegler CJ, Herrick RS, Rowlett RS Chem Commun (Camb). 2010 Feb 28;46(8):1203-5. Epub 2010 Jan 9. PMID:20449250[2] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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