CheckConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Categories: Catechol O-methyltransferase | Rattus norvegicus | Benz, J. | Ehler, A. | Rudolph, M G. | Schlatter, D. | Stihle, M. | Alternative initiation | Catecholamine metabolism | Cell membrane | Magnesium | Membrane | Metal-binding | Methyltransferase | Neurotransmitter degradation | Phosphoprotein | S-adenosyl-l-methionine | Signal-anchor | Transferase | Transmembrane