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|3b7x, resolution 2.10Å ()|
|Gene:||FKBP6, FKBP36 (Homo sapiens)|
Crystal structure of human FK506-Binding Protein 6
[FKBP6_HUMAN] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
[FKBP6_HUMAN] PPIases accelerate the folding of proteins.