Crystal structure of human FK506-Binding Protein 6
[FKBP6_HUMAN] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
[FKBP6_HUMAN] PPIases accelerate the folding of proteins.
About this Structure
3b7x is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Peptidylprolyl isomerase | Arrowsmith, C H. | Bochkarev, A. | Butler-Cole, C. | Davis, T. | Dhe-Paganon, S. | Edwards, A M. | Paramanathan, R. | SGC, Structural Genomics Consortium. | Walker, J R. | Weigelt, J. | Isomerase | Rotamase | Sgc | Structural genomics consortium | Tpr repeat | Williams-beuren syndrome