Structural highlights
Function
CHSP1_HUMAN Binds mRNA and regulates the stability of target mRNA. Binds single-stranded DNA (in vitro).[1] [2]
References
- ↑ Pfeiffer JR, McAvoy BL, Fecteau RE, Deleault KM, Brooks SA. CARHSP1 is required for effective tumor necrosis factor alpha mRNA stabilization and localizes to processing bodies and exosomes. Mol Cell Biol. 2011 Jan;31(2):277-86. doi: 10.1128/MCB.00775-10. Epub 2010 Nov, 15. PMID:21078874 doi:http://dx.doi.org/10.1128/MCB.00775-10
- ↑ Hou H, Wang F, Zhang W, Wang D, Li X, Bartlam M, Yao X, Rao Z. Structure-functional analyses of CRHSP-24 plasticity and dynamics in oxidative stress response. J Biol Chem. 2011 Mar 18;286(11):9623-35. Epub 2010 Dec 22. PMID:21177848 doi:http://dx.doi.org/10.1074/jbc.M110.177436