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From Proteopedia

2p1b, resolution 2.75Å ()
Domains:	Nucleoplasmin
Structural annotation: Resources: InterPro : Ipr004301 Pfam : PF03066 UniProt : P06748
Functional annotation: Cellular component: nucleolus nucleus centrosome cytoplasm Biological process: cell aging centrosome cycle response to stress signal transduction activation of NF-kappaB transcription factor negative regulation of cell proliferation intracellular protein transport nucleocytoplasmic transport ribosome assembly anti-apoptosis Molecular function: nucleic acid binding protein binding unfolded protein binding protein homodimerization activity RNA binding Tat protein binding protein heterodimerization activity transcription coactivator activity NF-kappaB binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Crystal structure of human nucleophosmin-core

About this Structure

2P1B is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Lee HH, Kim HS, Kang JY, Lee BI, Ha JY, Yoon HJ, Lim SO, Jung G, Suh SW. Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface. Proteins. 2007 Nov 15;69(3):672-8. PMID:17879352 doi:10.1002/prot.21504

Page seeded by OCA on Mon Feb 16 13:20:37 2009