Structural highlights
Function
[UBQL4_MOUSE] Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation.[1] [2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Li X, Su V, Kurata WE, Jin C, Lau AF. A novel connexin43-interacting protein, CIP75, which belongs to the UbL-UBA protein family, regulates the turnover of connexin43. J Biol Chem. 2008 Feb 29;283(9):5748-59. Epub 2007 Dec 13. PMID:18079109 doi:http://dx.doi.org/10.1074/jbc.M709288200
- ↑ Su V, Nakagawa R, Koval M, Lau AF. Ubiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75. J Biol Chem. 2010 Dec 24;285(52):40979-90. doi: 10.1074/jbc.M110.170753. Epub, 2010 Oct 12. PMID:20940304 doi:http://dx.doi.org/10.1074/jbc.M110.170753