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2j01
From Proteopedia
| 2j01, resolution 2.80Å () | |||||||||
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| Related: | 2j00, 2j02, 2j03, 1bxy, 1twv, 2b66, 2b9n, 2b9p | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.
The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.
Structure of the 70S ribosome complexed with mRNA and tRNA., Selmer M, Dunham CM, Murphy FV 4th, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V, Science. 2006 Sep 29;313(5795):1935-42. Epub 2006 Sep 7. PMID:16959973
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
2j01 is a 35 chain structure of Ribosomal protein L1, Ribosomal protein L10, Ribosomal protein L2, Ribosomal protein L3, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6, Ribosomal protein L7, Ribosomal protein L9 and Ribosome with sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
See Also
- Large Ribosomal Subunit of Haloarcula
- Ribosomal protein L1
- Ribosomal protein L10
- Ribosomal protein L2
- Ribosomal protein L3
- Ribosomal protein L4
- Ribosomal protein L5
- Ribosomal protein L6
- Ribosomal protein L7
- Ribosomal protein L9
- Ribosome
- User:Wayne Decatur/Haloarcula Large Ribosomal Subunit
Reference
- Selmer M, Dunham CM, Murphy FV 4th, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V. Structure of the 70S ribosome complexed with mRNA and tRNA. Science. 2006 Sep 29;313(5795):1935-42. Epub 2006 Sep 7. PMID:16959973
Categories: Thermus thermophilus | Dunham, C M. | Kelley, A C. | Murphy, F V. | Petry, S. | Ramakrishnan, V. | Selmer, M. | Weir, J R. | Weixlbaumer, A. | Mrna | Paromomycin | Ribosome | Translation | Trna
