Structural highlights
Function
[AUP1_HUMAN] May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Mueller B, Klemm EJ, Spooner E, Claessen JH, Ploegh HL. SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12325-30. doi:, 10.1073/pnas.0805371105. Epub 2008 Aug 18. PMID:18711132 doi:http://dx.doi.org/10.1073/pnas.0805371105
