2dhm

Structural highlights

Function

[BOLA_ECOLI] Plays an important role in general stress response (heat shock, acidic stress, oxidative stress, carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5), dacC (PBP6) and ampC.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

1. ↑ Santos JM, Freire P, Vicente M, Arraiano CM. The stationary-phase morphogene bolA from Escherichia coli is induced by stress during early stages of growth. Mol Microbiol. 1999 May;32(4):789-98. PMID:10361282
2. ↑ Santos JM, Lobo M, Matos AP, De Pedro MA, Arraiano CM. The gene bolA regulates dacA (PBP5), dacC (PBP6) and ampC (AmpC), promoting normal morphology in Escherichia coli. Mol Microbiol. 2002 Sep;45(6):1729-40. PMID:12354237