1z3a

Structural highlights

Function

TADA_ECOLI Deaminates adenosine-34 to inosine in tRNA-Arg2. Mutation in this protein makes E.coli resistant to the toxic proteins encoded by the gef gene family. Essential for cell viability.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• Adenosine deaminase 3D structures

References

1. ↑ Wolf J, Gerber AP, Keller W. tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli. EMBO J. 2002 Jul 15;21(14):3841-51. PMID:12110595 doi:http://dx.doi.org/10.1093/emboj/cdf362