Structural highlights
Function
DSCL1_HUMAN Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells (By similarity).[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Agarwala KL, Ganesh S, Tsutsumi Y, Suzuki T, Amano K, Yamakawa K. Cloning and functional characterization of DSCAML1, a novel DSCAM-like cell adhesion molecule that mediates homophilic intercellular adhesion. Biochem Biophys Res Commun. 2001 Jul 20;285(3):760-72. PMID:11453658 doi:http://dx.doi.org/10.1006/bbrc.2001.5214
