1ua7

From Proteopedia

Jump to: navigation, search


1ua7, resolution 2.21Å ()
Ligands: , , , , ,
Activity: Alpha-amylase, with EC number 3.2.1.1
Related: 1bag
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

Crystal Structure Analysis of Alpha-Amylase from Bacillus Subtilis complexed with Acarbose

Publication Abstract from PubMed

The crystal structure of Bacillus subtilis alpha-amylase, in complex with the pseudotetrasaccharide inhibitor acarbose, revealed an hexasaccharide in the active site as a result of transglycosylation. After comparison with the known structure of the catalytic-site mutant complexed with the native substrate maltopentaose, it is suggested that the present structure represents a mimic intermediate in the initial stage of the catalytic process.

Crystal structure of Bacillus subtilis alpha-amylase in complex with acarbose., Kagawa M, Fujimoto Z, Momma M, Takase K, Mizuno H, J Bacteriol. 2003 Dec;185(23):6981-4. PMID:14617662

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

About this Structure

1ua7 is a 1 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

See Also

Reference

  • Kagawa M, Fujimoto Z, Momma M, Takase K, Mizuno H. Crystal structure of Bacillus subtilis alpha-amylase in complex with acarbose. J Bacteriol. 2003 Dec;185(23):6981-4. PMID:14617662

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools