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1tf3
From Proteopedia
| 1tf3, 22 NMR models () | |||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES
The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.
Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA., Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE, Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1TF3 is a 3 chains structure of sequences from Xenopus laevis. Full experimental information is available from OCA.
Reference
- Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE. Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA. Nat Struct Biol. 1997 Aug;4(8):605-8. PMID:9253405
Page seeded by OCA on Tue Feb 17 13:24:30 2009
