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1s9k, resolution 3.10Å ()
Gene:	NFATC2, NFAT1, NFATP (Homo sapiens), FOS, G0S7 (Homo sapiens), JUN (Homo sapiens)
Domains:	IPT_NFAT, RHD
Related:	1a02, 1imh, 1a66, 1fos
Structural annotation: Resources: CATH : 1S9Kc02, 1S9Kc01, 1S9Kd00, 1S9Ke00 InterPro : Ipr008967, Ipr014756, Ipr008366, Ipr000451, Ipr002909, Ipr013783, Ipr011539, Ipr004827, Ipr000837, Ipr011700, Ipr011616, Ipr008917, Ipr015558, Ipr005643, Ipr002112 Pfam : PF00554, PF01833, PF07716, PF00170 UniProt : Q13469, P01100, P05412
Functional annotation: Resources: GeneCard : NFATC2, FOS, JUN Cellular component: nucleus cytoplasm transcription factor complex nuclear chromosome Biological process: regulation of transcription, DNA-dependent positive regulation of transcription cytokine production positive regulation of transcription from RNA polymerase II promoter regulation of transcription transcription regulation of transcription from RNA polymerase II promoter nervous system development DNA methylation inflammatory response negative regulation of protein amino acid autophosphorylation cellular process leading edge cell differentiation Molecular function: transcription activator activity transcription factor activity protein binding DNA binding specific RNA polymerase II transcription factor activity sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site

About this Structure

1S9K is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Tue Feb 17 21:10:59 2009