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1rq6
From Proteopedia
| 1rq6 () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene: | RPS17E, MTH803 (Methanothermobacter thermautotrophicus) | ||||||||
| Domains: | RPS17A | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB, TOPSAN | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Solution structure of ribosomal protein S17E from Methanobacterium Thermoautotrophicum, Northeast Structural Genomics Consortium Target TT802 / Ontario Center for Structural Proteomics Target Mth0803
The ribosomal protein S17E from the archaeon Methanobacterium thermoautotrophicum is a component of the 30S ribosomal subunit. S17E is a 62-residue protein conserved in archaea and eukaryotes and has no counterparts in bacteria. Mammalian S17E is a phosphoprotein component of eukaryotic ribosomes. Archaeal S17E proteins range from 59 to 79 amino acids, and are about half the length of the eukaryotic homologs which have an additional C-terminal region. Here we report the three-dimensional solution structure of S17E. S17E folds into a small three-helix bundle strikingly similar to the FF domain of human HYPA/FBP11, a novel phosphopeptide-binding fold. S17E bears a conserved positively charged surface acting as a robust scaffold for molecular recognition. The structure of M. thermoautotrophicum S17E provides a template for homology modeling of eukaryotic S17E proteins in the family.
The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain., Wu B, Yee A, Huang YJ, Ramelot TA, Cort JR, Semesi A, Jung JW, Lee W, Montelione GT, Kennedy MA, Arrowsmith CH, Protein Sci. 2008 Mar;17(3):583-8. Epub 2008 Jan 24. PMID:18218711
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1RQ6 is a 1 chain structure of sequence from Methanothermobacter thermautotrophicus. Full crystallographic information is available from OCA.
Reference
The solution structure of ribosomal protein S17E from Methanobacterium thermoautotrophicum: a structural homolog of the FF domain., Wu B, Yee A, Huang YJ, Ramelot TA, Cort JR, Semesi A, Jung JW, Lee W, Montelione GT, Kennedy MA, Arrowsmith CH, Protein Sci. 2008 Mar;17(3):583-8. Epub 2008 Jan 24. PMID:18218711
Page seeded by OCA on Fri Jan 2 09:13:18 2009
Categories: Methanothermobacter thermautotrophicus | Arrowsmith, C H. | Edward, A. | Huang, Y J. | Jung, J W. | Kennedy, M A. | Lee, W. | Montelione, G T. | NESG, Northeast Structural Genomics Consortium. | Ramelot, T A. | Semesi, A. | Wu, B. | Yee, A. | Alpha protein | Nesg | Northeast structural genomics consortium | Protein structure initiative | Psi | Structural genomic | Translation
