Structural highlights
Function
RBGA_BACSU Essential protein that is required for a late step of 50S ribosomal subunit assembly. Has GTPase activity that is stimulated by interaction with the immature 50S ribosome subunit. Binds to the 23S rRNA. Required for the association of ribosomal proteins RplP and RpmA with the large subunit.[1] [2] [3] [4]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Schaefer L, Uicker WC, Wicker-Planquart C, Foucher AE, Jault JM, Britton RA. Multiple GTPases participate in the assembly of the large ribosomal subunit in Bacillus subtilis. J Bacteriol. 2006 Dec;188(23):8252-8. Epub 2006 Sep 22. PMID:16997968 doi:http://dx.doi.org/JB.01213-06
- ↑ Matsuo Y, Morimoto T, Kuwano M, Loh PC, Oshima T, Ogasawara N. The GTP-binding protein YlqF participates in the late step of 50 S ribosomal subunit assembly in Bacillus subtilis. J Biol Chem. 2006 Mar 24;281(12):8110-7. Epub 2006 Jan 23. PMID:16431913 doi:http://dx.doi.org/M512556200
- ↑ Uicker WC, Schaefer L, Britton RA. The essential GTPase RbgA (YlqF) is required for 50S ribosome assembly in Bacillus subtilis. Mol Microbiol. 2006 Jan;59(2):528-40. PMID:16390447 doi:http://dx.doi.org/MMI4948
- ↑ Matsuo Y, Oshima T, Loh PC, Morimoto T, Ogasawara N. Isolation and characterization of a dominant negative mutant of Bacillus subtilis GTP-binding protein, YlqF, essential for biogenesis and maintenance of the 50 S ribosomal subunit. J Biol Chem. 2007 Aug 31;282(35):25270-7. Epub 2007 Jul 5. PMID:17613524 doi:http://dx.doi.org/M703894200