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From Proteopedia

1ntg, resolution 2.21Å ()
Gene:	YARS (Homo sapiens)
Activity:	Tyrosine--tRNA ligase, with EC number 6.1.1.1
Domains:	tRNA_bind_EMAP-II_like
Related:	1n3l
Structural annotation: Resources: CATH : 1Ntga00, 1Ntgb00, 1Ntgc00, 1Ntgd00 InterPro : Ipr002307, Ipr015624, Ipr001412, Ipr002305, Ipr012340, Ipr014729, Ipr002547 Pfam : PF01588 SCOP : d1ntga_, d1ntgb_, d1ntgc_, d1ntgd_ UniProt : P54577
Functional annotation: Resources: GeneCard : YARS Cellular component: soluble fraction extracellular space cytoplasm Biological process: tyrosyl-tRNA aminoacylation apoptosis tRNA aminoacylation for protein translation translation cell motility Molecular function: RNA binding tRNA binding interleukin-8 receptor binding tyrosine-tRNA ligase activity signal transducer activity ATP binding aminoacyl-tRNA ligase activity nucleotide binding ligase activity protein binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Crystal Structure of the EMAP II-like Cytokine Released from human tyrosyl-tRNA Synthetase

Disease

Known disease associated with this structure: Charcot-Marie-Tooth disease, dominant intermediate C OMIM:[603623]

About this Structure

1NTG is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Tue Feb 17 08:11:23 2009