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1nkw
From Proteopedia
Contents |
Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans
We describe the high resolution structure of the large ribosomal subunit from Deinococcus radiodurans (D50S), a gram-positive mesophile suitable for binding of antibiotics and functionally relevant ligands. The over-all structure of D50S is similar to that from the archae bacterium Haloarcula marismortui (H50S); however, a detailed comparison revealed significant differences, for example, in the orientation of nucleotides in peptidyl transferase center and in the structures of many ribosomal proteins. Analysis of ribosomal features involved in dynamic aspects of protein biosynthesis that are partially or fully disordered in H50S revealed the conformations of intersubunit bridges in unbound subunits, suggesting how they may change upon subunit association and how movements of the L1-stalk may facilitate the exit of tRNA.
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium., Harms J, Schluenzen F, Zarivach R, Bashan A, Gat S, Agmon I, Bartels H, Franceschi F, Yonath A, Cell. 2001 Nov 30;107(5):679-88. PMID:11733066
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1nkw is a 30 chain structure of Ribosomal protein L2, Ribosomal protein L3, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6, Ribosomal protein L9 and Ribosome with sequence from Deinococcus radiodurans. This structure supersedes the now removed PDB entries and 1kc9. Full crystallographic information is available from OCA.
See Also
- Large Ribosomal Subunit of Haloarcula
- Ribosomal protein L2
- Ribosomal protein L3
- Ribosomal protein L4
- Ribosomal protein L5
- Ribosomal protein L6
- Ribosomal protein L9
- Ribosome
- User:Wayne Decatur/Haloarcula Large Ribosomal Subunit
- User:Wayne Decatur/kink-turn motif
Reference
- Harms J, Schluenzen F, Zarivach R, Bashan A, Gat S, Agmon I, Bartels H, Franceschi F, Yonath A. High resolution structure of the large ribosomal subunit from a mesophilic eubacterium. Cell. 2001 Nov 30;107(5):679-88. PMID:11733066

