1iwa

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1iwa, resolution 2.60Å ()
Ligands:
Activity: Ribulose-bisphosphate carboxylase, with EC number 4.1.1.39
Related: 1bwv, 1ej7, 1ir1
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

RUBISCO FROM GALDIERIA PARTITA

Publication Abstract from PubMed

Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyzes the reactions of carboxylation and oxygenation of ribulose-1,5-bisphosphate. These reactions require that the active site should be closed by a flexible loop (loop 6) of the large subunit. Rubisco from a red alga, Galdieria partita, has the highest specificity for carboxylation reaction among the Rubiscos hitherto reported. The crystal structure of unactivated Galdieria Rubisco has been determined at 2.6 A resolution. The electron density map reveals that a sulfate binds only to the P1 anion-binding site of the active site and the loop 6 is closed. Galdieria Rubisco has a unique hydrogen bond between the main chain oxygen of Val332 on the loop 6 and the epsilon-amino group of Gln386 of the same large subunit. This interaction is likely to be crucial to understanding for stabilizing the loop 6 in the closed state and to making a higher affinity for anionic ligands.

X-ray structure of Galdieria Rubisco complexed with one sulfate ion per active site., Okano Y, Mizohata E, Xie Y, Matsumura H, Sugawara H, Inoue T, Yokota A, Kai Y, FEBS Lett. 2002 Sep 11;527(1-3):33-6. PMID:12220629

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

About this Structure

1iwa is a 16 chain structure with sequence from Galdieria partita. Full crystallographic information is available from OCA.

See Also

Reference

  • Okano Y, Mizohata E, Xie Y, Matsumura H, Sugawara H, Inoue T, Yokota A, Kai Y. X-ray structure of Galdieria Rubisco complexed with one sulfate ion per active site. FEBS Lett. 2002 Sep 11;527(1-3):33-6. PMID:12220629

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