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From Proteopedia

1gs9, resolution 1.70Å ()
Domains:	Apolipoprotein
Related:	1bz4, 1ea8, 1h7i, 1le2, 1le4, 1lpe, 1nfn, 1nfo, 1oef, 1oeg, 1or2, 1or3
Structural annotation: Resources: CATH : 1Gs9A00 InterPro : Ipr000074, Ipr013326 Pfam : PF01442 SCOP : d1gs9a_ UniProt : P02649
Functional annotation: Resources: GeneCard : APOE Cellular component: chylomicron extracellular region cytoplasm Biological process: intracellular transport cholesterol homeostasis synaptic transmission, cholinergic response to oxidative stress protein tetramerization lipid transport cytoskeleton organization and biogenesis learning and/or memory induction of apoptosis cholesterol catabolic process vasodilation cholesterol metabolic process regulation of neuronal synaptic plasticity lipoprotein metabolic process regulation of axon extension response to reactive oxygen species blood circulation transport cellular calcium ion homeostasis Molecular function: lipid binding tau protein binding beta-amyloid binding antioxidant activity phospholipid binding protein binding apolipoprotein E receptor binding heparin binding lipid transporter activity low-density lipoprotein receptor binding lipoprotein binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

APOLIPOPROTEIN E4, 22K DOMAIN

About this Structure

1GS9 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Wed Feb 18 05:31:29 2009