Structural highlights
Function
HEM1_METKA Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). In the absence of NADPH, exhibits substrate esterase activity, leading to the release of glutamate from tRNA.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Moser J, Lorenz S, Hubschwerlen C, Rompf A, Jahn D. Methanopyrus kandleri glutamyl-tRNA reductase. J Biol Chem. 1999 Oct 22;274(43):30679-85. PMID:10521455
