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1giy
From Proteopedia
| 1giy, resolution 5.50Å () | |||||||||
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| Related: | 486d, 1gix | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
CRYSTAL STRUCTURE OF THE RIBOSOME AT 5.5 A RESOLUTION. THIS FILE, 1GIY, CONTAINS THE 50S RIBOSOME SUBUNIT. THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES ARE IN THE FILE 1GIX
We describe the crystal structure of the complete Thermus thermophilus 70S ribosome containing bound messenger RNA and transfer RNAs (tRNAs) at 5.5 angstrom resolution. All of the 16S, 23S, and 5S ribosomal RNA (rRNA) chains, the A-, P-, and E-site tRNAs, and most of the ribosomal proteins can be fitted to the electron density map. The core of the interface between the 30S small subunit and the 50S large subunit, where the tRNA substrates are bound, is dominated by RNA, with proteins located mainly at the periphery, consistent with ribosomal function being based on rRNA. In each of the three tRNA binding sites, the ribosome contacts all of the major elements of tRNA, providing an explanation for the conservation of tRNA structure. The tRNAs are closely juxtaposed with the intersubunit bridges, in a way that suggests coupling of the 20 to 50 angstrom movements associated with tRNA translocation with intersubunit movement.
Crystal structure of the ribosome at 5.5 A resolution., Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Earnest TN, Cate JH, Noller HF, Science. 2001 May 4;292(5518):883-96. Epub 2001 Mar 29. PMID:11283358
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1giy is a 24 chain structure of Ribosomal protein L1, Ribosomal protein L2, Ribosomal protein L3, Ribosomal protein L4, Ribosomal protein L5, Ribosomal protein L6, Ribosomal protein L7 and Ribosome with sequence from Thermus thermophilus. Full crystallographic information is available from OCA.
See Also
- Ribosomal protein L1
- Ribosomal protein L2
- Ribosomal protein L3
- Ribosomal protein L4
- Ribosomal protein L5
- Ribosomal protein L6
- Ribosomal protein L7
- Ribosome
Reference
- Yusupov MM, Yusupova GZ, Baucom A, Lieberman K, Earnest TN, Cate JH, Noller HF. Crystal structure of the ribosome at 5.5 A resolution. Science. 2001 May 4;292(5518):883-96. Epub 2001 Mar 29. PMID:11283358 doi:10.1126/science.1060089
