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From Proteopedia

1ea8, resolution 1.95Å ()
Domains:	Apolipoprotein
Structural annotation: Resources: CATH : 1Ea8A00 InterPro : Ipr000074, Ipr013326 Pfam : PF01442 SCOP : d1ea8a_ UniProt : P02649
Functional annotation: Resources: GeneCard : APOE Cellular component: chylomicron extracellular region cytoplasm Biological process: cholesterol catabolic process response to oxidative stress vasodilation blood circulation cholesterol metabolic process regulation of neuronal synaptic plasticity transport cholesterol homeostasis learning and/or memory synaptic transmission, cholinergic regulation of axon extension intracellular transport response to reactive oxygen species cytoskeleton organization and biogenesis lipid transport lipoprotein metabolic process induction of apoptosis protein tetramerization cellular calcium ion homeostasis Molecular function: lipoprotein binding tau protein binding lipid binding phospholipid binding protein binding apolipoprotein E receptor binding antioxidant activity beta-amyloid binding low-density lipoprotein receptor binding heparin binding lipid transporter activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

APOLIPOPROTEIN E3 22KD FRAGMENT LYS146GLU MUTANT

About this Structure

1EA8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Tue Feb 17 16:41:12 2009