First time at Proteopedia? Click on the green links: they change the 3D image. Click and drag the molecules. Proteopedia is a 3D, interactive encyclopedia of proteins, RNA, DNA and other molecules. With a free user account, you can edit pages in Proteopedia. Visit the Main Page to learn more.
1bl0
From Proteopedia
| 1bl0, resolution 2.30Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene: | MARA (Escherichia coli) | ||||||||
| Domains: | PRK11511, HTH_AraC | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX
A crystal structure for a member of the AraC prokaryotic transcriptional activator family, MarA, in complex with its cognate DNA-binding site is described. MarA consists of two similar subdomains, each containing a helix-turn-helix DNA-binding motif. The two recognition helices of the motifs are inserted into adjacent major groove segments on the same face of the DNA but are separated by only 27 A thereby bending the DNA by approximately 35 degrees. Extensive interactions between the recognition helices and the DNA major groove provide the sequence specificity.
A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator., Rhee S, Martin RG, Rosner JL, Davies DR, Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:9724717
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
About this Structure
1BL0 is a 3 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Rhee S, Martin RG, Rosner JL, Davies DR. A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10413-8. PMID:9724717
Page seeded by OCA on Wed Feb 18 08:22:56 2009
