First time at Proteopedia? Click on the green links: they change the 3D image. Click and drag the molecules. Proteopedia is a 3D, interactive encyclopedia of proteins, RNA, DNA and other molecules. With a free user account, you can edit pages in Proteopedia. Visit the Main Page to learn more.

1aie

From Proteopedia

Jump to: navigation, search


1aie, resolution 1.50Å ()
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

P53 TETRAMERIZATION DOMAIN CRYSTAL STRUCTURE

Publication Abstract from PubMed

The molecular replacement method is a powerful technique for crystal structure solution but the use of NMR structures as templates often causes problems. In this work the NMR structure of the p53 tetramerization domain has been used to solve the crystal structure by molecular replacement. Since the rotation- and translation-functions were not sufficiently clear, additional information about the symmetry of the crystal and the protein complex was used to identify correct solutions. The three-dimensional structure of residues 326-356 was subsequently refined to a final R factor of 19.1% at 1.5 A resolution.

Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template., Mittl PR, Chene P, Grutter MG, Acta Crystallogr D Biol Crystallogr. 1998 Jan 1;54(Pt 1):86-9. PMID:9761820

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

About this Structure

1aie is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Mittl PR, Chene P, Grutter MG. Crystallization and structure solution of p53 (residues 326-356) by molecular replacement using an NMR model as template. Acta Crystallogr D Biol Crystallogr. 1998 Jan 1;54(Pt 1):86-9. PMID:9761820
  • Bhattacharyya R, Samanta U, Chakrabarti P. Aromatic-aromatic interactions in and around alpha-helices. Protein Eng. 2002 Feb;15(2):91-100. PMID:11917145
  • Alibes A, Yankilevich P, Canada A, Diaz-Uriarte R. IDconverter and IDClight: conversion and annotation of gene and protein IDs. BMC Bioinformatics. 2007 Jan 10;8:9. PMID:17214880 doi:10.1186/1471-2105-8-9

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://www.proteopedia.org/wiki/index.php/1aie"
Personal tools